Management Team

Dr Brian O’Keeffe - Chief Executive Officer

Brian O'KeefeeBrian brings more than 20 years of experience in research programme management in developing and testing pharmaceuticals as well as considerable international business experience and government-sponsored clinical research in the USA.

Formerly the regional medical director for Bayer Group in Asia, Brian was responsible for establishing a medical research and development organisation and incorporating key Asian countries into many of the company's new drug development programmes. Brian also served as president of Asia-Pacific business for Quintiles Transnational in Singapore, a large contract research organisation. Before becoming SimuGen's CEO, Brian was the Senior Vice President at the Malaysian Biotechnology Corporation.

Trained at British institutions, including London's Royal College of Surgeons, Brian also holds an M.B.A. from Birmingham University School of Business Studies. He is a member and Fellow of the Royal College of Physicians.

Matthijs van Leeuwen - Chief Operating Officer

Matthjis van LeeuwenMatthijs is SimuGen's co-founder and is responsible for the company's operational and business development activities.

In addition to his UK and Singaporean entrepreneurial activities, Matthijs has been very active as a consultant at the Cambridge-MIT Institute and Library House in Cambridge. Most recently he was a biotech analyst at London-based Imperial Innovations, one of Europe's leading technology commercialisation and investment companies.

Matthijs holds a B.Sc. in Biomedical Sciences and M.Sc. in Science & Business from the University of Utrecht, and gained research experience at the University of Cambridge.